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高惠陽
OFFICE: Department of Ophthalmology Tel# (513) 558-2802
College of Medicine University of Cincinnati Fax # (513) 558-3108
3223 Eden Avenue, M.L. 527
Cincinnati, OH 45267-0527
E-mail: Winston.Kao@UC.Edu
BIRTHPLACE: Tainan, Taiwan MARITAL STATUS: Married - Candace,
CITIZENSHIP: Naturalized U.S. Citizen
EDUCATION:
Location Degree Year Major
National Taiwan University B.S. 1966 Medical Technology
National Taiwan University M.S. 1970 Biochemistry
University of Pennsylvania Ph.D. 1974 Biochemistry
Rutgers Medical School CMDNJ Postdoctoral 1976 Biochemistry
PROFESSIONAL EXPERIENCE:
Sept. 2008-Present Ben and Louis Tate Chair Professor, Ophthalmology
Director, Crawley Vision Research Center
Member, All University Graduate Faculty at University of Cincinnati
Sept. 2001 Ben and Louis Tate Chair Professor, Ophthalmology
Director of Ophthalmic and Connective Tissue Research, University of Cincinnati
Member, All University Graduate Faculty at University of Cincinnati
Sept. 1990-2001 Professor of Ophthalmology
Director of Ophthalmic and Connective Tissue Research, University of Cincinnati
Member, All University Graduate Faculty at University of Cincinnati
Mechanism of Corneal Epithelial Cell Differentiation
Regulation of Extracellular Matrix Metabolism during Wound Healing
June 1982- Associate Professor, Department of Ophthalmology
August 1990 Director of Ophthalmic and Connective Tissue Research, Associate Professor in the Department of Ophthalmology, Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio
Member, All-University Graduate Faculty at University of Cincinnati, 1989
Develop ophthalmic research programs. Major research interests are the regulation of collagen gene expression during embryonic development and pathogenesis of ocular and pulmonary tissues.
Sept. 1979 - Assistant Professor, Department of Ophthalmology, University of Pittsburgh
June 1982 School of Medicine, Pittsburgh, Pennsylvania.
Purify and characterize prolyl hydroxylase from L-929 cells, human tissues and other sources. Purify mammalian collagenase to investigate the process of wound healing in cornea and immune response in microbial infections in the cornea. Purify and characterize procollagens and collagens and examine their synthesis in developing embryos and diseased tissues, and to investigate the mechanism of differentiation and gene expression in developing chick embryos.
1976-1979 Research Assistant Professor, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Same as above.
1975-1976 Research/Teaching Specialist III, CMDNJ-Rutgers Medical School, Department of Biochemistry, Piscataway, New Jersey.
In charge of the tissue culture laboratory in the department. Investigated collagen biosynthesis in primary cultures of tendon fibroblasts, cartilage cells, and established cell lines of fibroblasts (L-929). Especially interested in regulation of secretion of procollagen and metabolism of prolyl 4-hydroxylase. Developing new technique for quick easy radioimmune assay and general technique for cell cultures.
1972-1974 Research Fellow in CMDNJ- Rutgers Medical School, Department of Biochemistry, Piscataway, New Jersey.
Established laboratory of tissue culture in the department. Investigated the effects of ascorbic acid on the biosynthesis of procollagen by fibroblasts and on the activity of prolyl hydroxylase.
1970-1972 Research Assistant in the Department of Biochemistry School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Engaged in studies of the transport of sugar in mammalian cells and the methylation of ribosomal RNA in E. coli.
1968-1970 Graduate student in the Department of Biochemistry College of Medicine, National Taiwan University.
Investigated the effect of plant toxic proteins (such as abrin and ricin) on metabolism of normal and tumor cells.
1967-1968 Teaching Assistant, Department of Medical Technology College of Medicine, National Taiwan University.
AWARDS:
RPB - Robert E. McCormick Scholar (1986-1987).
RPB’s Senior Scientific Investigator (2003)
Visiting Professor
Chang Gung Medical College (March, 1993)
National Taiwan University (November, 98-March,31, 99)
University of Miami (April 1, -May 31, 1999)
PROFESSIONAL SOCIETIES:
Member, American Society of Biochemistry and Molecular Biology, 1982 - present
Member, Chinese Biochemistry Society, 1972 - present
Member, The Association for Research in Vision and Ophthalmology, 1976 - present
Member, American Association of Advanced Science, 1982 - present
Member, American Society of Cell Biology, 1996 - present
Member, International Society of Eye Research, 1987 - present
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